📄 Abstract
Avascular Necrosis (AVN), or osteonecrosis, is a progressive ischemic disorder characterised by compromised vascular supply leading to necrosis of bone and marrow elements, resulting in collapse and functional impairment, most commonly affecting the femoral head. In Ayurvedic parlance, it closely correlates with Asthi-Majjāgata Vāta, a Vāta-pradhāna vyādhi described in Charaka Saṃhitā, presenting with sandhiśūla (joint pain), māṃsa-bala-kṣaya (muscle wasting), and Asthiparva bheda (bony crepitus). The underlying pathology in both systems involves tissue depletion (dhātu-kṣaya) and obstruction of microchannels (srotorodha), analogous to ischemia and necrosis in modern understanding. Ācārya Charaka prescribes Mahāsneha—a formulation comprising taila, vasā, ghṛta, majjā, and kṣīra processed with Daśamūla, Rasnā, Chitraka, and Jīvanīya gaṇa—for Sirā-Majjā-Asthi-gata Vāta, providing deep nourishment, unctuousness, and Vāta-pacifying action. Therapeutic measures such as Snehana, Svedana, Basti, and Rasāyana chikitsā counteract dryness, promote regeneration, and enhance microcirculation, aligning conceptually with angiogenic and anti-inflammatory approaches in modern regenerative medicine. This integrative correlation suggests that AVN and Asthi-Majjāgata Vāta represent a common degenerative-ischemic continuum interpreted through different epistemological frameworks. Therefore, an integrative management approach combining Ayurvedic Snehana-Basti therapy and Rasāyana principles with modern regenerative modalities may offer synergistic benefits in restoring bone vitality, preventing collapse, and improving joint function.
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📚 How to Cite:
Dr. Nihal Gopan , Dr. Bharathi D Anvekar , Dr. Manjunath S Naregal , Dr Shankar S , A COMPREHENSIVE PERSPECTIVE OF AVASCULAR NECROSIS (AVN) AND ITS CLINICAL PARALLELS WITH ASTHI-MAJJAGATA VATA: TRADITIONAL INSIGHTS FROM MAHASNEHA AND SNEHANA CHIKITSA , Volume 11 , Issue 10, October 2025, EPRA International Journal of Multidisciplinary Research (IJMR) ,