📄 Abstract
Background Hip fracture is a major cause of disability, loss of independence, and mortality among older adults. In addition to the physical consequences of the fracture, psychological disorders, particularly depression, may negatively influence recovery. However, the magnitude of the association between depression and mortality after hip fracture and the mechanisms involved remain incompletely understood. Objective To analyze the available evidence regarding the association between depression and mortality after hip fracture and to explore potential mechanisms involving functional recovery, frailty, sarcopenia, nutritional status, cognitive impairment, delirium, and complications. Methods A narrative review of the literature was conducted using PubMed/MEDLINE, prioritizing publications from 2015 to 2026 and including earlier studies considered relevant to the topic. Observational studies, prospective and retrospective cohorts, longitudinal studies, systematic reviews, and meta-analyses were considered. The available evidence was synthesized qualitatively. Results Depression is common after hip fracture and may persist during the months following the event. Several studies have reported an association between depression or depressive symptoms and poorer functional recovery, although findings have not been consistent across populations. Other studies have reported an association between depressive symptoms and increased mortality, although the magnitude of the association varies according to the population studied, timing of assessment, and definition of depression. The relationship is likely multifactorial and may be influenced by immobility, loss of strength, functional decline, complications, and loss of autonomy. Conclusions Depression is a relevant biopsychosocial component of prognosis after hip fracture. Although current evidence supports an association with increased mortality, it does not establish depression as a direct cause of death. Depression may represent both a potentially modifiable condition and a marker of overall vulnerability. Early identification and multidisciplinary management may contribute to more comprehensive care, whereas future studies should determine whether treatment of depression can modify functional recovery and survival.
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📚 How to Cite:
Ana Belén Valero Martillo, David Sebastián Gómez Encalada, Mariela Guadalupe Loja Ávila, Bryam Esteban Coello García , DEPRESSION AND MORTALITY AFTER HIP FRACTURE: A NARRATIVE REVIEW OF CURRENT EVIDENCE , Volume 12 , Issue 9, September 2026, EPRA International Journal of Multidisciplinary Research (IJMR) , Pages: 572 - 577 , DOI: https://doi.org/10.36713/epra31601