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EVALUATION OF THE SIGNIFICANCE OF THE ARG506GLN POLYMORPHISM OF THE F5 GENE IN THE RISK OF MYOCARDIAL INFARCTION

📘 Volume 11 📄 Issue 9 📅 september 2025

👤 Authors

Khamidov Diyorbek Abdullayevich 1
1. Associate Professor of Andijan State Medical Institute, Propaedeutics of internal diseases, c. Andijan, Uzbekistan

📄 Abstract

In this study, we evaluated the association of Arg506Gln polymorphism of the F5 gene in the development of myocardial infarction (MI) in patients with COVID-19 coronavirus infection. A comparative analysis of the genotypes of the Arg506Gln polymorphism of the F5 gene in each subgroup of patients with MI yielded the following results. Compared with controls, a subgroup of patients with COVID-19 associated MI showed a significant increase in the content of the unfavorable Arg/Gln genotype (11.3% vs. 1.1% at χ2=7.5; p=0.01; OR=11, 4; 95% CI: 1.99-64.92), which represents a high risk of developing myocardial infarction, by 11.4 times.

🏷️ Keywords

Myocardial infarction COVID-19 Arg506Gln genetic polymorphism in the F5 gene

📚 How to Cite:

Khamidov Diyorbek Abdullayevich , EVALUATION OF THE SIGNIFICANCE OF THE ARG506GLN POLYMORPHISM OF THE F5 GENE IN THE RISK OF MYOCARDIAL INFARCTION , Volume 11 , Issue 9, september 2025, EPRA International Journal of Multidisciplinary Research (IJMR) ,

🔗 PDF URL

https://cdn.eprapublishing.org/article/202509-01-023969.pdf

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