📄 Abstract
TDDS is a painless method of delivering drugs systemically by applying a drug formulation onto intact and healthy skin. The drug initially penetrates through the stratum corneum and then passes through the deeper epidermis and dermis without drug accumulation in the dermal layer. A transdermal drug delivery system refers to a method of administering therapeutic drugs through the skin into the blood stream, for systemic effects. It involves the use of patches or devices that contain drug substances and facilitate their absorption. Compared to oral or systemic dosage systems, TDDS can offer a controlled release of the drugs through the skin into the patients, which could reduce the first-pass metabolism effects, lessen systemic side effects. Improve the dosage efficacy by enabling steadier blood drug profiles throughout the treatment, and enhance patient compliance. Transdermal drug delivery systems (TDDS) also known as ?patches? are dosage forms designed to deliver a therapeutically effective amount of drug across a patient?s skin. In order to deliver therapeutic agents through the human skin for systemic effects, the comprehensive morphological, biophysical and physicochemical properties of the skin are to be considered.
📚 How to Cite:
Prof. Gajanan. D. Mogal, Miss. Pallavi. B. Bawachkar, Mr. Mayur. S. Bhombe , FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES , Volume 11 , Issue 6, june 2025, EPRA International Journal of Multidisciplinary Research (IJMR) ,