📄 Abstract
Worldwide, excessive alcohol consumption is responsible for approximately 3.3 million deaths annually, accounting for 5.9% of all deaths (7.6% among men and 4.0% among women) and for approximately 139 million cases of disability [1,2]. Alcohol is a major risk factor in over 200 diseases, most of the deaths associated with it being caused by cardiovascular diseases, gastroenterological diseases (especially liver cirrhosis - LC) and various forms of cancer [1,3]. Chronic alcohol consumption affects the entire gastrointestinal system, with the liver being the most vulnerable organ, as it metabolizes over 90% of the alcohol consumed. Most ethanol is absorbed in the intestine (75%), in the stomach (22%) and only about 2% in the oral cavity and esophagus. This means that more than 90% of the absorbed alcohol circulates through the body and is eventually transported to the liver through the portal vein [7,8]. This process leads to the accumulation of toxic metabolites, overloading the hepatic enzyme systems. Alcoholic liver disease (ALD) is the most common pathology associated with alcohol consumption. If alcohol exposure is not stopped in time, liver damage becomes irreversible, with an increased lethal risk.
📚 How to Cite:
Gori?a Adriana, Bugai Rodica , LIVER CIRRHOSIS ASSOCIATED WITH ALCOHOL CONSUMPTION-LABORATORY PARTICULARITIES , Volume 11 , Issue 5, may 2025, EPRA International Journal of Multidisciplinary Research (IJMR) ,