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PHARMACOGNOSTIC INSIGHTS INTO THE ANTI-INFLAMMATORY AND ANALGESIC POTENTIAL OF Nelumbo nucifera LEAF EXTRACT

📘 Volume 12 📄 Issue 3 📅 March 2026

👤 Authors

Naazia Firdous Ansari, Priyanka Sharma 1
1. Department of Pharmacy, Barkatullah University, Department of Pharmacy, Bhopal, Madhya Pradesh, India

📄 Abstract

Nelumbo nucifera Gaertn., known as the sacred lotus, is an aquatic medicinal plant with significant traditional, cultural, and therapeutic importance in various Asian medical systems. Modern research has uncovered a range of bioactive compounds, such as aporphine alkaloids (like nuciferine), flavonoids (including quercetin derivatives and hyperoside), phenolic acids, and polysaccharides, which contribute to its antioxidant and anti-inflammatory properties (Bishayee et al., 2022; Tungmunnithum et al., 2018). Recent molecular studies show that lotus leaf extracts influence key inflammatory pathways like NF-?B, MAPK, and JNK, which help reduce the levels of pro-inflammatory substances such as TNF-a, IL-6, and nitric oxide (Liu et al., 2014; Kim et al., 2022). This review presents an overview of the botanical features, chemical composition, and pharmacological effects of N. nucifera leaves, with a focus on the pathways related to inflammation and pain management.

🏷️ Keywords

Nelumbo nucifera; Lotus leaf extract; Flavonoids; Hyperoside; Aporphine alkaloids; Anti-inflammatory activity; Analgesic potential; NF-?B signaling pathway; MAPK pathway; Oxidative stress; Phytochemical standardization

📚 How to Cite:

Naazia Firdous Ansari, Priyanka Sharma , PHARMACOGNOSTIC INSIGHTS INTO THE ANTI-INFLAMMATORY AND ANALGESIC POTENTIAL OF Nelumbo nucifera LEAF EXTRACT , Volume 12 , Issue 3, March 2026, EPRA International Journal of Multidisciplinary Research (IJMR) ,

🔗 PDF URL

https://cdn.eprapublishing.org/article/202603-01-026330.pdf

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