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A REVIEW ON MOLECULAR MECHANISM- TO STUDY DRUG LIPID INTERACTION

📘 Volume 9 📄 Issue 11 📅 november 2024

👤 Authors

Mr. Garad Vishvajit V, Mr. Rathod Laxman 1
1. Department of QA, Lokmangal College of Pharmacy, B pharmacy, Wadala, Solapur, Maharashtra, India

📄 Abstract

Since Singer and Nicolson's fluid mosaic model was introduced, our understanding of membrane organization has evolved. Rather than being homogeneous bilayers of lipids dispersed uniformly, plasma membranes are actually lipid complexes with laterally separated membrane domains, such as caveolae and lipid rafts. The pharmacokinetic features of medications, including their transport, distribution, and accumulation, ultimately impact their efficacy. Research conducted in both in vivo and cell culture settings has demonstrated the critical role that drug-lipid interactions play in these processes. Drug effectiveness can be estimated using liposome model membrane systems in a variety of ways. Estimating the quantity of drug carried into cells as well as its route of transport is also possible with lipid model membranes.

📚 How to Cite:

Mr. Garad Vishvajit V, Mr. Rathod Laxman , A REVIEW ON MOLECULAR MECHANISM- TO STUDY DRUG LIPID INTERACTION , Volume 9 , Issue 11, november 2024, EPRA International Journal of Research & Development (IJRD) ,

🔗 PDF URL

https://cdn.eprapublishing.org/article/202411-02-019199.pdf

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