📄 Abstract
Abdominal aortic aneurysm (AAA) is a progressive vascular disorder characterized by abnormal dilatation of the abdominal aorta, defined as a diameter of ≥3 cm or more than 50% above normal. It is a potentially life-threatening condition due to the risk of rupture, leading to severe internal bleeding and high mortality. AAA commonly affects elderly individuals, especially males, and is strongly associated with risk factors such as smoking, hypertension, atherosclerosis, dyslipidemia, and genetic predisposition. The pathogenesis involves inflammation, extracellular matrix degradation, oxidative stress, and vascular smooth muscle cell loss, resulting in weakening of the aortic wall. Most AAAs remain asymptomatic and are often detected incidentally through imaging techniques such as ultrasonography and CT scan. . Management strategies depend on aneurysm size, growth rate, and patient risk factors, ranging from regular surveillance to surgical interventions such as open surgical repair and endovascular aneurysm repair (EVAR). Early screening and appropriate therapeutic interventions are essential to reduce morbidity and mortality associated with AAA.
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📚 How to Cite:
Kokkula Himasri, Dr. Syeda Nishat Fathima , ABDOMINAL AORTIC ANEURYSM: CURRENT INSIGHTS INTO RISK FACTORS, PATHOGENESIS, DIAGNOSTIC STRATEGIES, AND THERAPEUTIC APPROACHES , Volume 11 , Issue 8, August 2026, EPRA International Journal of Research & Development (IJRD) , Pages: 147 - 153 , DOI: https://doi.org/10.36713/epra28902