📄 Abstract
Imeglimin is a novel molecule currently under development for the treatment of type 2 diabetes mellitus, and is the first agent of the ?glimin? class of glucose-lowering medication. It has a unique mechanism of action that targets the three main pathophysiologic components of type 2 diabetes: impaired glucose uptake by muscle tissue, excess hepatic gluconeogenesis and increased ß-cell apoptosis. To date, imeglimin has been evaluated in many preclinical and clinical trials and has shown to have notable antihyperglycaemic effects, such as statistically significant reductions in glycated haemoglobin, fasting plasma glucose and other glycaemic parameters. The encouraging tolerability profile, combined with its efficacy, could make it suitable as a monotherapy or in combination with other classes of antidiabetic agents, hopefully in the near future.
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📚 How to Cite:
Singh Aryan Pankaj, Dr. Khushi Patel, Dr. Ishika Prajapati, Dr. Bhoomkia Yadav, Dr Riya Mishra , IMEGLIMIN: A REVIEW , Volume 10 , Issue 1, january 2025, EPRA International Journal of Research & Development (IJRD) , DOI: https://doi.org/10.36713/epra19749